Unlock the Secrets to Strategic Drug Product Design: Formulation Strategies Across the DCS

Due to the increasing complexity of new molecular therapies, acceleration of clinical development timelines and significant limitations of existing formulation technologies, there is a need for "outside the box" approaches to obtaining acceptable exposure. This means formulators not only need to bring scientific excellence, but also strategy to enable effective development of these programs.

This talk explores two different case studies of drug product design that center around a scientific understanding of molecular properties to design enabled formulations that are scalable and advanceable from the start.

Key Takeaways:

Defining the problem statements early is key to guiding:
- Formulation strategies
- Technology selection
Balancing the four pillars of formulation can help identify the most appropriate technology that enables robust formulations
By developing right from the start, programs can rapidly progress through the phases of development

View On Demand

Wesley Tatum, PhD

Principal Engineer, Process and Product Development

Wesley Tatum is a Principal Engineer in the Process and Product Development department at Serán. He leads a team of scientists and engineers in characterizing new API and identifying shortcomings for bioavailability. He and his team then screen and select drug product intermediates that address those shortcomings and screen and scale up drug product formulations. During his time at Serán, his work and research has focused on understanding how polymers, excipients, and physiological factors influence speciation, bioavailability, and absorption of drug substances and amorphous solid dispersions.

Wesley holds undergraduate degrees in Physics and Physical Chemistry from Whitworth University and a Ph.D. in Materials Science and Engineering from the University of Washington.

About Serán

Serán's Science-First Approach

Serán Bioscience is a science-based CDMO that specializes in a variety of drug delivery and formulation approaches suited to optimizing bioavailability. Our experienced formulation team will work with you to identify an appropriate technology and formulation strategy to meet your program’s unique needs. We take a comprehensive approach to formulation design that considers the physiochemical properties of the API, the target product profile, and your program’s objectives and constraints to develop scalable formulations using efficient and material-sparing approaches.

What Our Customers Are Saying

Delivering you the simplest approach to meet your program's needs.

When I think of Solubility Problems, I think of Serán.

Consultant

Consultant, Multiple Clients

Make a batch on time. Reliable CDMO, quality product within the timelines.

Large Pharma

Customers come for the flexibility and stay for the dedication.

Small Biotech

I’ve been impressed with Serán. One of the things we really look for is flexibility. They are a good combination of flexibility and technical competence.

Medium Size Pharma

The scientists we met at Serán were top notch.